Artebabe Artesunate 250 mg Chewable Tablets for Dogs
Artebabe Tablets contain Artesunate IP 250 mg, a derivative of artemisinin used in veterinary treatment protocols for babesiosis. The product is intended for veterinarian-supervised combination treatment of selected protozoal infections in dogs.
Artesunate is described in the supplied product information as acting against parasites through free-radical generation and disruption of parasite membrane structures.
<bold>Veterinary Prescription Required | For Veterinary Use Only</bold>
Product Overview
Artebabe is an oral chewable veterinary tablet containing:
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Active Ingredient: Artesunate IP
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Strength: 250 mg per tablet
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Dosage Form: Chewable tablet
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Route: Oral administration
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Pack Size: 10 × 1 × 10 tablets
Key Features & Benefits
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Artesunate-Based Formula: Contains Artesunate, a derivative of artemisinin used in the treatment of babesiosis.
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Veterinary Antiprotozoal Use: Intended for inclusion in veterinarian-directed treatment protocols for selected protozoal infections.
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Combination Treatment Protocols: The supplied product information mentions its use alongside other veterinary medicines in the management of relapsing babesiosis and mixed infections.
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Oral Chewable Format: Designed for oral administration and may be given whole or split as required for the prescribed dose.
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Defined Active Strength: Each uncoated chewable tablet contains 250 mg Artesunate IP.
Composition
Each uncoated chewable tablet contains:
| Ingredient |
Strength |
| Artesunate IP |
250 mg |
Indications
According to the supplied product information, Artebabe is indicated as part of combination treatment protocols for:
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Relapsing babesiosis in dogs.
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Mixed infections involving Babesia canis.
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Babesia gibsoni infection.
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Ehrlichia canis infection.
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Anaplasma platys infection.
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Hepatozoon canis infection.
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Tick-fever cases involving mixed infections.
The source mentions combination protocols involving Artebabe, Atavon-Pro, Macrozee and, in certain cases, Imidopet.
Important: These are source-listed treatment indications. The veterinarian must diagnose the infection and decide whether this medicine and any combination therapy are appropriate.
Pharmacodynamics
The action of Artesunate is described as depending on activation involving iron-mediated cleavage of the endoperoxide bridge of DHA. This generates unstable organic free radicals, followed by alkylation. The free radicals bind to parasite proteins, leading to destruction of parasite membranes.
Pharmacokinetics
According to the supplied product information:
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Artesunate is a water-soluble derivative of artemisinin.
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It is rapidly absorbed and extensively, almost completely, hydrolysed to its active metabolite DHA before reaching systemic circulation.
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Absorption of DHA after oral dosing takes approximately one hour.
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The elimination half-life of artesunate is less than three hours, while that of DHA is less than one hour.
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Oral bioavailability of artesunate is stated to be up to 60%.
Dosage & Administration
The supplied product information lists:
Artesunate: 12.5 mg/kg body weight, once daily for 10 days, through the oral route.
The amount of tablet required must be calculated by the veterinarian according to the dog's body weight and prescribed treatment plan.
Do not calculate or administer the dose independently. The 250 mg tablet strength does not mean that one complete tablet is suitable for every dog.
Directions for Use
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Administer orally as prescribed by the veterinarian.
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The tablet may be given whole or split as required for the prescribed dose.
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Ensure that the complete prescribed dose is consumed.
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Avoid over-dosing or under-dosing.
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Follow the complete treatment schedule prescribed by the veterinarian.
Mode of Action
Artesunate acts by inhibiting heme polymerization, generating reactive oxygen species (ROS), destabilizing the parasite membrane and inhibiting PfATP6, according to the supplied product information.
Possible Side Effects
The supplied product information lists the following possible side effects:
The tablet may be fed by hand or placed on food. The source advises monitoring the dog during and for several minutes after administration. Coughing may be observed in some animals.
Contact your veterinarian if your pet develops unusual symptoms or a suspected adverse reaction.
Warnings & Precautions
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Use only under veterinary supervision.
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Do not exceed or reduce the prescribed dose independently.
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Ensure that the dog consumes the complete prescribed dose.
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Monitor your pet during and after administration.
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Inform the veterinarian about other medicines being administered.
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Do not use this product as a substitute for veterinary diagnosis and treatment.
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Keep out of reach of children.
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Not for human use.
Storage Instructions
Store in a cool, dry place at room temperature. Keep the medicine out of reach of children.
Product Specifications
| Specification |
Details |
| Brand |
Artebabe |
| Active Ingredient |
Artesunate IP |
| Strength |
250 mg per tablet |
| Category |
Veterinary Antiprotozoal |
| Dosage Form |
Chewable Tablets |
| Intended Animal |
Dogs |
| Administration |
Oral |
| Pack Configuration |
10 × 1 × 10 Tablets |
| MRP |
₹400 per 10 tablets |
| Prescription |
Required |
| Storage |
Cool, dry place at room temperature |
Frequently Asked Questions
1. What is Artebabe 250 mg used for?
Artebabe contains Artesunate and is listed in the supplied product information for veterinarian-supervised combination treatment protocols for babesiosis and selected mixed infections in dogs.
2. What is the composition of Artebabe?
Each uncoated chewable tablet contains Artesunate IP 250 mg.
3. What is the dosage mentioned for Artebabe?
The supplied product information lists 12.5 mg/kg body weight once daily for 10 days by the oral route. The veterinarian must determine the actual tablet quantity and treatment plan.
4. Can Artebabe be used with Atavon-Pro?
The supplied product literature mentions Artebabe and Atavon-Pro together in certain combination treatment protocols. Use this combination only when specifically prescribed by a veterinarian.
5. Can the tablet be split?
The supplied directions state that the tablet may be given whole or split as required for administration.
6. Is Artebabe suitable for self-medication?
No. It is a veterinary medicine and should only be used following veterinary diagnosis and prescription.
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FOR VETERINARY USE ONLY. NOT FOR HUMAN USE. USE ONLY UNDER VETERINARY PRESCRIPTION.
