Frontline Plus Spot-On for Dogs is a scientifically advanced topical ectoparasitic treatment designed to provide comprehensive protection against fleas, ticks, and biting lice. Formulated with a dual-action combination of Fipronil (adulticide) and (S)-Methoprene (insect growth regulator), it effectively eliminates existing infestations while preventing reinfestation by disrupting the flea life cycle at all stages.
This veterinary prescription product is highly effective in controlling flea infestations for up to 8 weeks and ticks for up to 4 weeks. It also helps manage Flea Allergy Dermatitis (FAD), a common skin condition caused by flea bites in dogs. The formula works through contact action, spreading across the skin and haircoat within 24 hours of application without requiring absorption into the bloodstream.
Manufactured by Boehringer Ingelheim Animal Health France, Frontline Plus is a globally trusted solution recommended by veterinarians for reliable and long-lasting parasite control.
Key Benefits
- Dual-action formula kills adult fleas, ticks, and lice
- Stops flea life cycle by eliminating eggs, larvae, and pupae
- Kills fleas within 24 hours and ticks within 48 hours
- Provides up to 8 weeks of flea protection
- Provides up to 4 weeks of tick control
- Helps in the management of Flea Allergy Dermatitis (FAD)
- Waterproof formula (avoid bathing for 48 hours post-application)
- Spreads naturally across the skin via sebaceous glands
- Safe for use in pregnant and lactating dogs
Composition
- Fipronil – 9.8% w/v
- (S)-Methoprene – 8.8% w/v
Indications
- Treatment and prevention of flea infestations (Ctenocephalides spp.)
- Control of tick infestations (Ixodes ricinus, Dermacentor spp., Rhipicephalus sanguineus)
- Treatment of biting lice (Trichodectes canis)
- Prevention of flea multiplication through ovicidal and larvicidal action
- Management of Flea Allergy Dermatitis (FAD)
Dosage & Administration
Minimum Dose:
- Fipronil: 6.7 mg/kg
- (S)-Methoprene: 6 mg/kg
Dosage by Weight:
- 2–10 kg → 0.67 ml (Small)
- 10–20 kg → 1.34 ml (Medium)
- 20–40 kg → 2.68 ml (Large)
- 40–60 kg → 4.02 ml (Extra Large)
Method of Application:
- Remove one pipette from the foil pack
- Hold upright and snap the tip
- Part fur at the base of the neck (between the shoulder blades)
- Apply the entire contents directly on the skin in one spot
Only one pipette per treatment is required.
Contraindications
- Not for puppies below 8 weeks or under 2 kg
- Do not use on sick or recovering animals
- Do not use in rabbits (may cause fatal reactions)
- Do not use in cats (risk of overdose)
- Minimum treatment interval: 4 weeks
Possible Side Effects
- Rare skin reactions (itching, redness, hair loss)
- Temporary coat changes (greasy/clumped hair)
- Excessive salivation if licked
- Rare neurological signs or vomiting
Consult a veterinarian if any adverse effects are observed.
Warnings & Precautions
- For external veterinary use only
- Not for human use
- Use only under veterinary prescription (RMP)
- Avoid contact with eyes, mouth, and skin
- Do not allow pets to lick the treated area
- Keep away from children until dry
- Avoid bathing for 48 hours after application
- Do not allow dogs to swim in water bodies for 2 days
- Wash your hands after use
Pharmacological Action
-
Fipronil: Disrupts GABA-regulated chloride channels, causing parasite death
-
(S)-Methoprene: Mimics juvenile hormone to inhibit flea development
Together, they ensure the complete eradication of parasites and environmental control.
Storage
- Store below 30°C
- Keep in original packaging
- Protect from moisture and sunlight
- Shelf life: 36 months
Product Information
- Brand: Frontline Plus
- Manufacturer: Boehringer Ingelheim Animal Health France SCS
- Imported by: Boehringer Ingelheim India Pvt Ltd
- Country of Origin: France
- Form: Spot-On Solution
- Suitable For: Dogs
