Intas Nayflee Plus is a dual-action monthly flea and tick spot-on treatment for dogs, combining Fipronil 9.8% w/v with (S)-Methoprene 8.8% w/v, an Insect Growth Regulator (IGR), in a single pipette applied to the back of the neck once a month. Fipronil kills adult fleas, ticks and lice on contact, while S-Methoprene prevents flea eggs and larvae from developing into breeding adults, helping to break the flea reinfestation cycle rather than only addressing the visible adult population. Nayflee Plus is also indicated for the management of flea allergy dermatitis and acaral lick dermatitis in dogs, and is safe from 8 weeks of age. It is available in 4 pipette sizes to suit different dog weights, from NUVO, a division of Intas Pharmaceuticals Ltd.
KEY FEATURES
- Contains Fipronil 9.8% w/v and (S)-Methoprene 8.8% w/v (IGR)
- Dual-action: kills adult fleas, ticks and lice, and disrupts flea egg/larval development
- Monthly spot-on application
- Indicated for flea allergy dermatitis and acaral lick dermatitis management
- Safe from 8 weeks of age
- Available in 4 pipette sizes based on dog weight
BENEFITS
Fipronil blocks GABA-gated chloride channels in the nervous systems of adult fleas, ticks and lice, causing hyperexcitation, paralysis and death within hours of contact, and continues to be released from the sebaceous glands onto the coat surface for up to 4 weeks, providing lasting residual protection. S-Methoprene, a juvenile hormone analogue, mimics the natural hormone that keeps immature fleas in their larval stage, preventing flea eggs and larvae — both on the dog and those that fall into the environment (carpets, bedding, floor cracks) — from developing into breeding adults. Together, this combination is intended to deliver both immediate adult flea/tick/lice control and longer-term flea lifecycle disruption in a single monthly application, which can be particularly relevant for dogs with recurring flea problems. Consistent monthly use is also intended to help manage flea allergy dermatitis by reducing flea exposure in hypersensitive dogs, and to support management of acaral lick dermatitis associated with mite activity.
COMPOSITION / INGREDIENTS
Fipronil — 9.8% w/v
(S)-Methoprene — 8.8% w/v
INDICATIONS / USES
- Flea treatment and lifecycle control (adults, eggs and larvae)
- Tick control
- Lice control
- Flea allergy dermatitis (FAD) management
- Acaral lick dermatitis management
DIRECTIONS FOR USE
Select the correct pipette size for your dog's bodyweight:
- Up to 10 kg: 0.67 ml
- 10–20 kg: 1.34 ml
- 20–40 kg: 2.68 ml
- Above 40 kg: 4.02 ml
Never use a smaller pipette applied multiple times to make up the dose — always use the single pipette corresponding to your dog's weight. If your dog is between sizes, use the larger pipette and consult your veterinarian.
Part the fur at the base of the neck, between the shoulder blades, where your dog cannot reach to lick. Snap or twist the pipette tip open. For dogs up to 20 kg, apply the entire contents directly onto the skin in one spot. For dogs above 20 kg, apply across 2–3 spots along the spine for better distribution. Do not rub in — allow the solution to spread naturally through the coat via the sebaceous glands. Keep your dog dry and avoid bathing for at least 48 hours after application. Apply once every month for continuous protection.
SAFETY INFORMATION
Safe from 8 weeks of age. For external use on dogs. Not provided / Not verified — pregnancy/lactation safety and specific contraindications were not detailed in the supplied information and should be confirmed from the product label before use.
STORAGE
Store according to the manufacturer's instructions.
PRODUCT DETAILS
- Brand: Nayflee Plus (NUVO, a division of Intas Pharmaceuticals Ltd.)
- Product Name: Nayflee Plus Spot On
- Product Type: Dual-action ectoparasiticide spot-on (Fipronil + IGR)
- Species: Dogs
- Active Ingredients: Fipronil 9.8% w/v, (S)-Methoprene 8.8% w/v
- Pack Sizes: 0.67 ml, 1.34 ml, 2.68 ml, 4.02 ml pipettes
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Product information prepared by PetsLifestyle & Vɪsʜɴᴜ Dᴜᴛᴛ Tʀɪᴘᴀᴛʜɪ | Pᴇᴛ Exᴘᴇʀᴛ, based on the product information available from the manufacturer/brand.
FAQs
What does Nayflee Plus treat?
It treats and controls fleas (including eggs and larvae), ticks and lice in dogs, and is also indicated for managing flea allergy dermatitis and acaral lick dermatitis.
What are the active ingredients?
It contains Fipronil 9.8% w/v and (S)-Methoprene 8.8% w/v, an Insect Growth Regulator.
How is Nayflee Plus different from a plain Fipronil spray?
It includes S-Methoprene, which stops flea eggs and larvae from developing into breeding adults, addressing the flea lifecycle rather than just the visible adult fleas.
How often is Nayflee Plus applied?
Once a month, as a spot-on application to the back of the neck.
What pipette size should I use for my dog?
Up to 10 kg: 0.67 ml. 10–20 kg: 1.34 ml. 20–40 kg: 2.68 ml. Above 40 kg: 4.02 ml. If your dog is between sizes, use the larger pipette and consult your vet.
Is Nayflee Plus safe for puppies?
Yes, it is stated to be safe from 8 weeks of age.
