Vetina Levetiracetam 500 mg Tablets are a broad-spectrum anticonvulsant medication formulated to help manage epilepsy and seizure disorders in dogs and cats. Levetiracetam belongs to the pyrrolidine class of antiepileptic drugs and is widely used either as monotherapy or as an adjunctive treatment in companion animals suffering from recurrent seizures.
Levetiracetam works by reducing abnormal electrical activity in the brain without significantly affecting normal neuronal transmission. Unlike many traditional antiepileptic drugs, it has minimal interaction with voltage-dependent sodium channels, GABA receptors, and glutamate receptors. Its primary mechanism involves selective binding to synaptic vesicle protein SV2A, helping regulate neurotransmitter release and stabilise neuronal activity.
Vetina Levetiracetam is particularly useful in dogs that are inadequately controlled with phenobarbital or bromides, or in animals that cannot tolerate these medications. Clinical evidence also suggests that adding levetiracetam to dogs experiencing phenobarbital-associated liver toxicity may allow a reduction in phenobarbital dosage without increasing seizure frequency. It may also serve as an effective add-on therapy in cats with epilepsy.
Levetiracetam is generally well tolerated and offers veterinarians an important therapeutic option for long-term seizure management in companion animals.
Available at PᴇᴛsLɪғᴇsᴛʏʟᴇ, India's trusted online pet pharmacy and destination for veterinary neurological medications and pet healthcare products.
COMPOSITION
Each film-coated tablet contains
Levetiracetam IP – 500 mg
Excipients – Quantity sufficient
BENEFITS
• Broad-spectrum anticonvulsant for epilepsy management
• Helps control focal, partial-complex, and generalised seizures
• Useful in dogs refractory to phenobarbital and bromide therapy
• Can be used as monotherapy or adjunctive treatment
• Selectively binds to synaptic vesicle protein SV2A
• Modulates synaptic release of glutamate and GABA
• May help reduce phenobarbital dosage in dogs with liver toxicity
• Well tolerated in both dogs and cats
• Minimal interaction with other anticonvulsant pathways
• Supports long-term seizure control and improved quality of life
FEEDING GUIDE
Dosage should be determined by a veterinarian based on the patient's condition and response to therapy.
Dogs
As an add-on treatment for epilepsy refractory to phenobarbital and bromides
20 mg/kg orally every 8 hours
Alternative dosage range
7.1–23.8 mg/kg orally every 8 hours
Initially
10–20 mg/kg orally every 8 hours
Dose may be increased in 20 mg/kg increments until adequate seizure control is achieved.
Cats
As an add-on to phenobarbital therapy
Initially, 20 mg/kg orally three times daily
FAQ
What is Vetina Levetiracetam used for?
Vetina Levetiracetam is used to manage epilepsy and seizure disorders in dogs and cats.
Can Levetiracetam be given with phenobarbital?
Yes. It is commonly used alongside phenobarbital, especially in pets with poorly controlled seizures.
Is Levetiracetam safe for cats?
Yes. Levetiracetam has a wide safety margin in cats and is often used as adjunct therapy for feline epilepsy.
Are there any side effects?
Levetiracetam is generally well tolerated. Mild behavioural changes, vomiting, gastrointestinal disturbances, or temporary loss of appetite may occasionally occur.
Can pets with kidney disease receive Levetiracetam?
Use with caution in animals with renal impairment, as dose adjustments or changes in dosing frequency may be necessary.
OTHER DETAILS
Brand
Vetina
Product Type
Antiepileptic and Anticonvulsant Medication
Suitable For
Dogs and Cats
Life Stage
Adult Pets
Senior Pets
Indications
Focal epilepsy
Partial-complex epilepsy
Generalized epilepsy
Prevention and management of seizures
Adjunct therapy with phenobarbital or bromides
Mechanism of Action
Selective binding to synaptic vesicle protein SV2A
Modulates glutamate and GABA neurotransmitter release
Possible inhibition of high-voltage-regulated calcium channels
Administration
Oral
Pack Size
1 × 10 Tablets
Storage Instructions
Store in a cool and dry place below 25°C. Protect from moisture and direct sunlight.